SILVER: intensity-based scoring and visualization of tandem mass spectra
Introduction to SILVER
SILVER allows you to upload spectrum (DTA) files, and view them in the light
of a LOD-based scoring scheme, indicating which peaks are
surprising, either by their presence or by their absence.
To refer to the algorithm implemented on this website,
please cite these two publications:
one for the algorithm, one for its implementation in this site:
- Elias, J.E., Gibbons, F.D., King, O.D., Roth, F.P., and Gygi, S.P.
Intensity-based protein identifiation by machine learning
from a library of tandem mass spectra.,
Nat. Biotech. vol. 22, pp214-219
Gibbons, F.D., Elias, J.E., Gygi, S.P., and Roth, F.P. (2004)
SILVER helps assign peptides to tandem mass spectra
using intensity-based scoring. J. Am. Soc. Mass Spectrom. (accepted)